Molecule of the Month
May 2024

CFTR and Cystic Fibrosis

Cystic fibrosis is currently treated using drugs that enhance the function of mutated CFTR

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Use PDB-101 resources to learn about the structural biology of athletics and well-being
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The RCSB PDB Curricula provide authentic, hands-on teaching materials, individual and group activities and assessment suggestions
SciArt Galleries
Irving Geis (1908-1997) was a gifted artist who helped illuminate the field of structural biology with his iconic images. The Geis Digital Archive features many of his illustrations in the context of their molecular structures.

Images used with permission from the Howard Hughes Medical Institute (www.hhmi.org). All rights reserved.

Carboxypeptidase A

Z-DNA

DNA

Cytochrome c

Hemoglobin (1000)

Deoxyribonucleic Acid (DNA)

Intermolecular Contacts in Hemoglobin S

Hemoglobin S

Myoglobin Fold

B-DNA

DPG-Hemoglobin Complex

Induced Lac Repressor

Aspartate Transcarbamoylase (ATCase)

Myohemerythrin

TATA-Binding Protein (TBP)

Immunoglobulin G (IgG)

Lac Repressor

Myoglobin

Lysozyme (512)

Lysozyme (488)

Cytochrome c (unbound)

Ribonuclease S

Tomato Bushy Stunt Virus (TBSV)

Oxyhemoglobin

Crambin

Transfer Ribonucleic Acid (tRNA)

Collagen

Deoxyhemoglobin

Trypsin

Hemoglobin

A-DNA

The Molecular Landscapes by David S. Goodsell integrate information from structural biology, microscopy and biophysics to simulate detailed views of the molecular structure of living cells.

Illustrations are free for use under a CC-BY-4.0 license

Collagen and Extracellular Matrix

Insulin Action

HIV Vaccine

Abiogenesis

Vascular Endothelial Growth Factor (VegF) Signaling

SARS-CoV-2 and Neutralizing Antibodies

Poliovirus Neutralization

Phage-based COVID-19 Vaccine

SARS-CoV-2 mRNA Vaccine

Autophagy

Myoglobin in a Whale Muscle Cell

Mycoplasma mycoides

Coronavirus

SARS-CoV-2 Fusion

HIV-Infected Cell

JCVI-syn3A Minimal Cell

Escherichia coli

Biosites: Cytoplasm

Biosites: Red Blood Cell

Coronavirus Life Cycle

Respiratory Droplet

Ebola Virus

Measles Virus Proteins

Biosites: Blood Plasma

Insulin Release

Excitatory and Inhibitory Synapses

Caulobacter Polar Microdomain

Lipid Droplets

Biosites: Muscle

Influenza Vaccine

Bacteriophage T4 Infection

Last Universal Common Ancestor

Blood

Transfer RNA and Gag Protein

Chloroplast

Myelin

HIV in Blood Plasma

CytoSkeleton

Biosites: Basement Membrane

RecA and DNA

Immunological Synapse

Cellulose Synthase

Casein Micelle and Fat Globule in Milk

Escherichia coli Bacterium

Biosites: Nucleus

Red Blood Cell Cytoskeleton

Model of a Mycoplasma Cell

Zika Virus